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Autophagy and misfolded proteins in neurodegeneration
The accumulation of misfolded proteins in insoluble aggregates within the neuronal cytoplasm is one of the common pathological hallmarks of most adult-onset human neurodegenerative diseases. The clearance of these misfolded proteins may represent a promising therapeutic strategy in these diseases. T...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Academic Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463804/ https://ncbi.nlm.nih.gov/pubmed/21095248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.11.003 |
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