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Autophagy, a guardian against neurodegeneration

Autophagy is an intracellular degradation process responsible for the clearance of most long-lived proteins and organelles. Cytoplasmic components are enclosed by double-membrane autophagosomes, which subsequently fuse with lysosomes for degradation. Autophagy dysfunction may contribute to the patho...

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Detalhes bibliográficos
Main Authors: García-Arencibia, Moisés, Hochfeld, Warren E., Toh, Pearl P.C., Rubinsztein, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938570/
https://ncbi.nlm.nih.gov/pubmed/20188203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2010.02.008
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