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The Identification of Histidine 712 as a Critical Residue for Constitutive TRPV5 Internalization
The epithelial Ca(2+) channel TRPV5 constitutes the apical entry gate for Ca(2+) transport in renal epithelial cells. Ablation of the trpv5 gene in mice leads to a reduced Ca(2+) reabsorption. TRPV5 is tightly regulated by various calciotropic hormones, associated proteins, and other factors, which...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937873/ https://ncbi.nlm.nih.gov/pubmed/20628046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.117143 |
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