Molecular Mechanisms of Calmodulin Action on TRPV5 and Modulation by Parathyroid Hormone

The epithelial Ca(2+) channel transient receptor potential vanilloid 5 (TRPV5) constitutes the apical entry gate for active Ca(2+) reabsorption in the kidney. Ca(2+) influx through TRPV5 induces rapid channel inactivation, preventing excessive Ca(2+) influx. This inactivation is mediated by the last...

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Main Authors: de Groot, Theun, Kovalevskaya, Nadezda V., Verkaart, Sjoerd, Schilderink, Nathalie, Felici, Marco, van der Hagen, Eline A. E., Bindels, René J. M., Vuister, Geerten W., Hoenderop, Joost G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133394/
https://ncbi.nlm.nih.gov/pubmed/21576356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01319-10
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