Parathyroid Hormone Activates TRPV5 via PKA-Dependent Phosphorylation

Low extracellular calcium (Ca(2+)) promotes release of parathyroid hormone (PTH), which acts on multiple organs to maintain overall Ca(2+) balance. In the distal part of the nephron, PTH stimulates active Ca(2+) reabsorption via the adenylyl cyclase–cAMP–protein kinase A (PKA) pathway, but the molec...

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Detalhes bibliográficos
Main Authors: de Groot, Theun, Lee, Kyupil, Langeslag, Michiel, Xi, Qi, Jalink, Kees, Bindels, René J.M., Hoenderop, Joost G.J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723979/
https://ncbi.nlm.nih.gov/pubmed/19423690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008080873
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