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A Gate Hinge Controls the Epithelial Calcium Channel TRPV5
TRPV5 is unique within the large TRP channel family for displaying a high Ca(2+) selectivity together with Ca(2+)-dependent inactivation. Our study aims to uncover novel insights into channel gating through in-depth structure-function analysis. We identify an exceptional tryptophan (W583) at the ter...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379628/ https://ncbi.nlm.nih.gov/pubmed/28374795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45489 |
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