β1-Adrenergic Receptor Signaling Activates the Epithelial Calcium Channel, Transient Receptor Potential Vanilloid Type 5 (TRPV5), via the Protein Kinase A Pathway

Epinephrine and norepinephrine are present in the pro-urine. β-Adrenergic receptor (β-AR) blockers administered to counteract sympathetic overstimulation in patients with congestive heart failure have a negative inotropic effect, resulting in reduced cardiac contractility. Positive inotropes, β1-AR...

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Autors principals: van der Hagen, Eline A. E., Tudpor, Kukiat, Verkaart, Sjoerd, Lavrijsen, Marla, van der Kemp, Annemiete, van Zeeland, Femke, Bindels, René J. M., Hoenderop, Joost G. J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Membrane Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140292/
https://ncbi.nlm.nih.gov/pubmed/24828496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491274
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