The Epithelial Calcium Channel TRPV5 Is Regulated Differentially by Klotho and Sialidase

The transient receptor potential vanilloid type 5 (TRPV5) Ca(2+) channel facilitates transcellular Ca(2+) transport in the distal convoluted tubule (DCT) of the kidney. The channel is glycosylated with a complex type N-glycan and it has been postulated that hydrolysis of the terminal sialic acid(s)...

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Main Authors: Leunissen, Elizabeth H. P., Nair, Anil V., Büll, Christian, Lefeber, Dirk J., van Delft, Floris L., Bindels, René J. M., Hoenderop, Joost G. J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Membrane Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795225/
https://ncbi.nlm.nih.gov/pubmed/23970553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473520
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