TMPRSS2 and TMPRSS4 Facilitate Trypsin-Independent Spread of Influenza Virus in Caco-2 Cells

Proteolysis of influenza virus hemagglutinin by host cell proteases is essential for viral infectivity, but the proteases responsible are not well defined. Recently, we showed that engineered expression of the type II transmembrane serine proteases (TTSPs) TMPRSS2 and TMPRSS4 allows hemagglutinin (H...

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Bibliografiska uppgifter
Huvudupphovsmän: Bertram, Stephanie, Glowacka, Ilona, Blazejewska, Paulina, Soilleux, Elizabeth, Allen, Paul, Danisch, Simon, Steffen, Imke, Choi, So-Young, Park, Youngwoo, Schneider, Heike, Schughart, Klaus, Pöhlmann, Stefan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937781/
https://ncbi.nlm.nih.gov/pubmed/20631123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00239-10
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