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miR-375 Inhibits Differentiation of Neurites by Lowering HuD Levels

Neuronal development and plasticity are maintained by tightly regulated gene expression programs. Here, we report that the developmentally regulated microRNA miR-375 affects dendrite formation and maintenance. miR-375 overexpression in mouse hippocampus potently reduced dendrite density. We identifi...

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Autors principals: Abdelmohsen, Kotb, Hutchison, Emmette R., Lee, Eun Kyung, Kuwano, Yuki, Kim, Mihee M., Masuda, Kiyoshi, Srikantan, Subramanya, Subaran, Sarah S., Marasa, Bernard S., Mattson, Mark P., Gorospe, Myriam
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937556/
https://ncbi.nlm.nih.gov/pubmed/20584986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00316-10
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