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Convergent Transcription through a Long CAG Tract Destabilizes Repeats and Induces Apoptosis

Short repetitive sequences are common in the human genome, and many fall within transcription units. We have previously shown that transcription through CAG repeat tracts destabilizes them in a way that depends on transcription-coupled nucleotide excision repair and mismatch repair. Recent observati...

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Détails bibliographiques
Auteurs principaux: Lin, Yunfu, Leng, Mei, Wan, Ma, Wilson, John H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937530/
https://ncbi.nlm.nih.gov/pubmed/20647539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00332-10
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