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Convergent Transcription through a Long CAG Tract Destabilizes Repeats and Induces Apoptosis

Short repetitive sequences are common in the human genome, and many fall within transcription units. We have previously shown that transcription through CAG repeat tracts destabilizes them in a way that depends on transcription-coupled nucleotide excision repair and mismatch repair. Recent observati...

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Detalhes bibliográficos
Main Authors: Lin, Yunfu, Leng, Mei, Wan, Ma, Wilson, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937530/
https://ncbi.nlm.nih.gov/pubmed/20647539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00332-10
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