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Convergent Transcription through a Long CAG Tract Destabilizes Repeats and Induces Apoptosis
Short repetitive sequences are common in the human genome, and many fall within transcription units. We have previously shown that transcription through CAG repeat tracts destabilizes them in a way that depends on transcription-coupled nucleotide excision repair and mismatch repair. Recent observati...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937530/ https://ncbi.nlm.nih.gov/pubmed/20647539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00332-10 |
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