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De Novo Identification and Biophysical Characterization of Transcription Factor Binding Sites with Microfluidic Affinity Analysis

Gene expression is regulated in part by protein transcription factors (TFs) that bind target regulatory DNA sequences. Predicting DNA binding sites and affinities from transcription factor sequence or structure is difficult; therefore, experimental data are required to link TFs to target sequences....

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Bibliografische gegevens
Hoofdauteurs: Fordyce, Polly M., Gerber, Doron, Tran, Danh, Zheng, Jiashun, Li, Hao, DeRisi, Joseph L., Quake, Stephen R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937095/
https://ncbi.nlm.nih.gov/pubmed/20802496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1675
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