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Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses

A quantitative understanding of how transcription factors interact with genomic target sites is crucial for reconstructing transcriptional networks in vivo. Here, we use Hac1, a well-characterized basic leucine zipper (bZIP) transcription factor involved in the unfolded protein response (UPR) as a m...

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Detalhes bibliográficos
Main Authors: Fordyce, Polly M., Pincus, David, Kimmig, Philipp, Nelson, Christopher S., El-Samad, Hana, Walter, Peter, DeRisi, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494901/
https://ncbi.nlm.nih.gov/pubmed/23054834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212457109
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