Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid

It is difficult to overestimate the importance of nucleoside triphosphates in cellular chemistry: They are the building blocks for DNA and RNA and important sources of energy. Modifications of biologically important organic molecules with fluorine are of great interest to chemists and biologists bec...

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Main Authors: Surya Prakash, G. K., Zibinsky, Mikhail, Upton, Thomas G., Kashemirov, Boris A., McKenna, Charles E., Oertell, Keriann, Goodman, Myron F., Batra, Vinod K., Pedersen, Lars C., Beard, William A., Shock, David D., Wilson, Samuel H., Olah, George A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
Assuntos:
Physical Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936638/
https://ncbi.nlm.nih.gov/pubmed/20724659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007430107
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