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Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid

It is difficult to overestimate the importance of nucleoside triphosphates in cellular chemistry: They are the building blocks for DNA and RNA and important sources of energy. Modifications of biologically important organic molecules with fluorine are of great interest to chemists and biologists bec...

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Autori principali: Surya Prakash, G. K., Zibinsky, Mikhail, Upton, Thomas G., Kashemirov, Boris A., McKenna, Charles E., Oertell, Keriann, Goodman, Myron F., Batra, Vinod K., Pedersen, Lars C., Beard, William A., Shock, David D., Wilson, Samuel H., Olah, George A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936638/
https://ncbi.nlm.nih.gov/pubmed/20724659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007430107
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