12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

Protein tyrosine phosphatases (PTPs) are regulated through reversible oxidation of the active-site cysteine. Previous studies have implied soluble reactive oxygen species (ROS), like H(2)O(2), as the mediators of PTP oxidation. The potential role(s) of peroxidized lipids in PTP oxidation have not be...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Conrad, Marcus, Sandin, Åsa, Förster, Heidi, Seiler, Alexander, Frijhoff, Jeroen, Dagnell, Markus, Bornkamm, Georg W., Rådmark, Olof, van Huijsduijnen, Rob Hooft, Aspenström, Pontus, Böhmer, Frank, Östman, Arne
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936618/
https://ncbi.nlm.nih.gov/pubmed/20798033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007909107
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi