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Ubiquitin/SUMO Modification Regulates VHL Protein Stability and Nucleocytoplasmic Localization
Functional inactivation of the von Hippel-Lindau (VHL) tumor suppressor protein is linked to the development of several forms of cancer as well as oncogenic progression like sporadic renal clear-cell carcinomas (RCC). Despite the critical role played by VHL in destruction of hypoxia-inducible factor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Public Library of Science
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936558/ https://ncbi.nlm.nih.gov/pubmed/20844582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012636 |
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