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SUMO-Modification of Human Nrf2 at K(110) and K(533) Regulates Its Nucleocytoplasmic Localization, Stability and Transcriptional Activity
BACKGROUND/AIMS: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that binds to the antioxidant response element(s) (ARE) in target gene promoters, enabling oxidatively stressed cells to respond in order to restore redox homeostasis. Post-translational modifications (PTMs...
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| Gepubliceerd in: | Cell Physiol Biochem |
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| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8279473/ https://ncbi.nlm.nih.gov/pubmed/33770425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33594/000000351 |
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