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A conserved arginine near the filter of Kir1.1 controls Rb/K selectivity

ROMK (Kir1.1) channels are important for K secretion and recycling in the collecting duct, connecting tubule and thick ascending limb of the mammalian nephron. We have identified a highly conserved Arg in the P loop of the channel near the selectivity filter that controls Rb/K selectivity. Mutation...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Sackin, Henry, Nanazashvili, Mikheil, Li, Hui, Palmer, Lawrence G., Walters, D. Eric
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935938/
https://ncbi.nlm.nih.gov/pubmed/20458182
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