Llwytho...

Human prion strain selection in transgenic mice

Transgenic (Tg) mice expressing chimeras of mouse and human prion proteins (PrP) have shorter incubation periods for Creutzfeldt-Jakob disease (CJD) prions than mice expressing full-length human PrP. Increasing the sequence similarity of the chimeric PrP to mouse PrP, by reverting human residues to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Giles, Kurt, Glidden, David V., Patel, Smita, Korth, Carsten, Groth, Darlene, Lemus, Azucena, DeArmond, Stephen J., Prusiner, Stanley B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935907/
https://ncbi.nlm.nih.gov/pubmed/20695008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22104
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