Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin

Novel therapeutic agents that are safe and effective are needed for the treatment of pancreatic, ovarian, lung adenocarcinomas and mesotheliomas. Mesothelin is a glycosyl-phosphatidyl inositol (GPI)-linked membrane protein of 40 kDa over-expressed in all pancreatic adenocarcinoma and mesothelioma, i...

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Autors principals: Hassan, Raffit, Ebel, Wolfgang, Routhier, Eric L., Patel, Rina, Kline, J. Bradford, Zhang, Jingli, Chao, Qimin, Jacob, Sara, Turchin, Howard, Gibbs, Lester, Phillips, Martin D., Mudali, Shiyama, Iacobuzio-Donahue, Christine, Jaffee, Elizabeth M., Moreno, Maria, Pastan, Ira, Sass, Philip M., Nicolaides, Nicholas C., Grasso, Luigi
Format: Artigo
Idioma:Inglês
Publicat: Academy of Cancer Immunology 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935758/
https://ncbi.nlm.nih.gov/pubmed/18088084
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