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Phase I Clinical Trial of the Chimeric Anti-Mesothelin Monoclonal Antibody MORAb-009 in Patients with Mesothelin Expressing Cancers

PURPOSE: MORAb-009 is a chimeric monoclonal antibody that targets mesothelin, a tumor differentiation antigen over-expressed in pancreatic cancer, ovarian cancer, mesothelioma and other malignancies. We conducted a Phase I clinical trial of MORAb-009 in patients with advanced mesothelin expressing c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hassan, Raffit, Cohen, Steven J., Phillips, Martin, Pastan, Ira, Sharon, Elad, Kelly, Ronan J., Schweizer, Charles, Weil, Susan, Laheru, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057907/
https://ncbi.nlm.nih.gov/pubmed/21037025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2275
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