Inhibition of mesothelin-CA-125 interaction in patients with mesothelioma by the anti-mesothelin monoclonal antibody MORAb-009: implications for cancer therapy

BACKGROUND: Mesothelin, a tumor differentiation antigen highly expressed in mesothelioma and ovarian cancer, is the receptor for CA-125 (MUC 16) and this interaction may play a role in tumor metastasis. MORAb-009 is a chimeric anti-mesothelin monoclonal antibody. METHODS: Twenty-four patients with m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hassan, Raffit, Schweizer, Charles, Lu, Kun F., Schuler, Barbara, Remaley, Alan T., Weil, Susan C., Pastan, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864325/
https://ncbi.nlm.nih.gov/pubmed/19744744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2009.07.016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados