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Tumor and organ uptake of (64)Cu-labeled MORAb-009 (amatuximab), an anti-mesothelin antibody, by PET Imaging and biodistribution studies

OBJECTIVES: To investigate the effect of the injection dose of MORAb-009 (amatuximab, an anti-mesothelin monoclonal antibody), the tumor size and the level of shed mesothelin on the uptake of the antibody in mesothelin-positive tumor and organs by biodistribution (BD) and positron emission tomograph...

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Detalhes bibliográficos
Publicado no:Nucl Med Biol
Main Authors: Lee, Jae-Ho, Kim, Heejung, Yao, Zhengsheng, Lee, Sung-Jin, Szajek, Lawrence P, Grasso, Luigi, Pastan, Ira, Paik, Chang H
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593745/
https://ncbi.nlm.nih.gov/pubmed/26307499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2015.07.008
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