Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors.

SR 49059, a new potent and selective orally active, nonpeptide vasopressin (AVP) antagonist has been characterized in several in vitro and in vivo models. SR 49059 showed high affinity for V1a receptors from rat liver (Ki = 1.6 +/- 0.2) and human platelets, adrenals, and myometrium (Ki ranging from...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Serradeil-Le Gal, C, Wagnon, J, Garcia, C, Lacour, C, Guiraudou, P, Christophe, B, Villanova, G, Nisato, D, Maffrand, J P, Le Fur, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC293574/
https://ncbi.nlm.nih.gov/pubmed/8392086
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi