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A new crystal form of Lys48-linked diubiquitin

Lys48-linked polyubiquitin chains are recognized by the proteasome as a tag for the degradation of the attached substrates. Here, a new crystal form of Lys48-linked diubiquitin (Ub(2)) was obtained and the crystal structure was refined to 1.6 Å resolution. The structure reveals an ordered isopeptide...

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Autori principali: Trempe, Jean-François, Brown, Nicholas R., Noble, Martin E. M., Endicott, Jane A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935213/
https://ncbi.nlm.nih.gov/pubmed/20823512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110027600
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