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Conformational Dynamics of Wild-type Lys-48-linked Diubiquitin in Solution
Proteasomal degradation is mediated through modification of target proteins by Lys-48-linked polyubiquitin (polyUb) chain, which interacts with several binding partners in this pathway through hydrophobic surfaces on individual Ub units. However, the previously reported crystal structures of Lys-48-...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199495/ https://ncbi.nlm.nih.gov/pubmed/21900242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256354 |
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