Conformational Dynamics of Wild-type Lys-48-linked Diubiquitin in Solution

Proteasomal degradation is mediated through modification of target proteins by Lys-48-linked polyubiquitin (polyUb) chain, which interacts with several binding partners in this pathway through hydrophobic surfaces on individual Ub units. However, the previously reported crystal structures of Lys-48-...

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Hlavní autoři: Hirano, Takashi, Serve, Olivier, Yagi-Utsumi, Maho, Takemoto, Emi, Hiromoto, Takeshi, Satoh, Tadashi, Mizushima, Tsunehiro, Kato, Koichi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Molecular Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199495/
https://ncbi.nlm.nih.gov/pubmed/21900242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256354
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