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Structural basis of redox-dependent substrate binding of protein disulfide isomerase

Protein disulfide isomerase (PDI) is a multidomain enzyme, operating as an essential folding catalyst, in which the b′ and a′ domains provide substrate binding sites and undergo an open–closed domain rearrangement depending on the redox states of the a′ domain. Despite the long research history of t...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Yagi-Utsumi, Maho, Satoh, Tadashi, Kato, Koichi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563560/
https://ncbi.nlm.nih.gov/pubmed/26350503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13909
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