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Structural basis of redox-dependent substrate binding of protein disulfide isomerase

Protein disulfide isomerase (PDI) is a multidomain enzyme, operating as an essential folding catalyst, in which the b′ and a′ domains provide substrate binding sites and undergo an open–closed domain rearrangement depending on the redox states of the a′ domain. Despite the long research history of t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Yagi-Utsumi, Maho, Satoh, Tadashi, Kato, Koichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563560/
https://ncbi.nlm.nih.gov/pubmed/26350503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13909
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