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Structural basis of redox-dependent substrate binding of protein disulfide isomerase

Protein disulfide isomerase (PDI) is a multidomain enzyme, operating as an essential folding catalyst, in which the b′ and a′ domains provide substrate binding sites and undergo an open–closed domain rearrangement depending on the redox states of the a′ domain. Despite the long research history of t...

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Publicat a:Sci Rep
Autors principals: Yagi-Utsumi, Maho, Satoh, Tadashi, Kato, Koichi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563560/
https://ncbi.nlm.nih.gov/pubmed/26350503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13909
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