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Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer
PURPOSE: STAT3 (signal transducer and activator of transcription-3) is downstream of growth factor and cytokine receptors and regulates key oncogenic pathways in non-small cell lung cancer (NSCLC). Activation of STAT3 by c-Src promotes tumor progression. We hypothesized that c-Src inhibition could a...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935176/ https://ncbi.nlm.nih.gov/pubmed/19861436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0767 |
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