Aerosol Therapy with Colistin Methanesulfonate: a Biopharmaceutical Issue Illustrated in Rats

The aim of this study was to evaluate the biopharmaceutical behavior of colistin methanesulfonate (CMS) with special focus on colistin presystemic formation after CMS nebulization in rats. CMS was administered (15 mg·kg(−1) of body weight) either intravenously for systemic pharmacokinetic studies (n...

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Detaylı Bibliyografya
Asıl Yazarlar: Marchand, Sandrine, Gobin, Patrice, Brillault, Julien, Baptista, Sara, Adier, Christophe, Olivier, Jean-Christophe, Mimoz, Olivier, Couet, William
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934989/
https://ncbi.nlm.nih.gov/pubmed/20547787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00411-10
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