NagZ Inactivation Prevents and Reverts β-Lactam Resistance, Driven by AmpD and PBP 4 Mutations, in Pseudomonas aeruginosa

AmpC hyperproduction is the most frequent mechanism of resistance to penicillins and cephalosporins in Pseudomonas aeruginosa and is driven by ampD mutations or the recently described inactivation of dacB, which encodes the nonessential penicillin-binding protein (PBP) PBP 4. Recent work showed that...

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Detaylı Bibliyografya
Asıl Yazarlar: Zamorano, Laura, Reeve, Thomas M., Deng, Lehua, Juan, Carlos, Moyá, Bartolomé, Cabot, Gabriel, Vocadlo, David J., Mark, Brian L., Oliver, Antonio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934985/
https://ncbi.nlm.nih.gov/pubmed/20566764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00385-10
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