NagZ Inactivation Prevents and Reverts β-Lactam Resistance, Driven by AmpD and PBP 4 Mutations, in Pseudomonas aeruginosa

AmpC hyperproduction is the most frequent mechanism of resistance to penicillins and cephalosporins in Pseudomonas aeruginosa and is driven by ampD mutations or the recently described inactivation of dacB, which encodes the nonessential penicillin-binding protein (PBP) PBP 4. Recent work showed that...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zamorano, Laura, Reeve, Thomas M., Deng, Lehua, Juan, Carlos, Moyá, Bartolomé, Cabot, Gabriel, Vocadlo, David J., Mark, Brian L., Oliver, Antonio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934985/
https://ncbi.nlm.nih.gov/pubmed/20566764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00385-10
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