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AmpG Inactivation Restores Susceptibility of Pan-β-Lactam-Resistant Pseudomonas aeruginosa Clinical Strains

Constitutive AmpC hyperproduction is the most frequent mechanism of resistance to the weak AmpC inducers antipseudomonal penicillins and cephalosporins. Previously, we demonstrated that inhibition of the β-N-acetylglucosaminidase NagZ prevents and reverts this mechanism of resistance, which is cause...

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Bibliografische gegevens
Hoofdauteurs: Zamorano, Laura, Reeve, Thomas M., Juan, Carlos, Moyá, Bartolomé, Cabot, Gabriel, Vocadlo, David J., Mark, Brian L., Oliver, Antonio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088256/
https://ncbi.nlm.nih.gov/pubmed/21357303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01688-10
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