Pan-β-Lactam Resistance Development in Pseudomonas aeruginosa Clinical Strains: Molecular Mechanisms, Penicillin-Binding Protein Profiles, and Binding Affinities

We investigated the mechanisms leading to Pseudomonas aeruginosa pan-β-lactam resistance (PBLR) development during the treatment of nosocomial infections, with a particular focus on the modification of penicillin-binding protein (PBP) profiles and imipenem, ceftazidime, and ceftolozane (former CXA-1...

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Detalhes bibliográficos
Main Authors: Moyá, Bartolomé, Beceiro, Alejandro, Cabot, Gabriel, Juan, Carlos, Zamorano, Laura, Alberti, Sebastián, Oliver, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421878/
https://ncbi.nlm.nih.gov/pubmed/22733064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00680-12
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