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Catalytic Cycle of the N‑Acetylglucosaminidase NagZ from Pseudomonas aeruginosa

The N-acetylglucosaminidase NagZ of Pseudomonas aeruginosa catalyzes the first cytoplasmic step in recycling of muropeptides, cell-wall-derived natural products. This reaction regulates gene expression for the β-lactam resistance enzyme, β-lactamase. The enzyme catalyzes hydrolysis of N-acetyl-β-d-g...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Acebrón, Iván, Mahasenan, Kiran V., De Benedetti, Stefania, Lee, Mijoon, Artola-Recolons, Cecilia, Hesek, Dusan, Wang, Huan, Hermoso, Juan A., Mobashery, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873925/
https://ncbi.nlm.nih.gov/pubmed/28482153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01626
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