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An evaluation of the role of properdin in alternative pathway activation on Neisseria meningitidis and Neisseria gonorrhoeae

Properdin, a positive regulator of the alternative pathway (AP) of complement is important in innate immune defenses against invasive Neisserial infections. Recently, commercially-available unfractionated properdin was shown to bind to certain biological surfaces, including Neisseria gonorrhoeae, wh...

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Detalhes bibliográficos
Main Authors: Agarwal, Sarika, Ferreira, Viviana P., Cortes, Claudio, Pangburn, Michael K., Rice, Peter A., Ram, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933790/
https://ncbi.nlm.nih.gov/pubmed/20530262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903598
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