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Native Polymeric Forms of Properdin Selectively Bind to Targets and Promote Activation of the Alternative Pathway of Complement

Properdin, a positive regulator of the complement system, has recently been reported to bind to certain pathogenic microorganisms, to early or late apoptotic and necrotic cells, and to particular live human cell lines, thus providing a platform for de novo convertase assembly and complement activati...

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Detalhes bibliográficos
Main Authors: Ferreira, Viviana P., Cortes, Claudio, Pangburn, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949450/
https://ncbi.nlm.nih.gov/pubmed/20382442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2010.02.002
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