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Local release of properdin in the cellular microenvironment: role in pattern recognition and amplification of the alternative pathway of complement
Properdin, the only positive regulatory protein of the complement system, acts as both a stabilizer of the alternative pathway (AP) convertases and as a selective pattern recognition molecule of certain microorganisms and host cells (i.e., apoptotic/necrotic cells) by serving as a platform for de no...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3547370/ https://ncbi.nlm.nih.gov/pubmed/23335922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00412 |
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