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Linkage Specificity and Role of Properdin in Activation of the Alternative Complement Pathway by Fungal Glycans

Fungal cell walls are predominantly composed of glucans, mannans, and chitin. Recognition of these glycans by the innate immune system is a critical component of host defenses against the mycoses. Complement, an important arm of innate immunity, plays a significant role in fungal pathogenesis, espec...

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Hlavní autoři: Agarwal, Sarika, Specht, Charles A., Huang, Haibin, Ostroff, Gary R., Ram, Sanjay, Rice, Peter A., Levitz, Stuart M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163941/
https://ncbi.nlm.nih.gov/pubmed/21878570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00178-11
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