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Exploiting fungal cell wall components in vaccines

Innate recognition of fungi leads to strong adaptive immunity. Investigators are trying to exploit this observation in vaccine development by combining antigens with evolutionarily conserved fungal cell wall carbohydrates to induce protective responses. Best studied is β-1,3-glucan, a glycan that ac...

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Bibliographic Details
Published in:Semin Immunopathol
Main Authors: Levitz, Stuart M., Huang, Haibin, Ostroff, Gary R., Specht, Charles A.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329074/
https://ncbi.nlm.nih.gov/pubmed/25404118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-014-0460-6
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