INVESTIGATING THE STRUCTURAL INFLUENCE OF SURFACE MUTATIONS ON ACETYLCHOLINESTERASE INHIBITON BY ORGANOPHOSPHORUS COMPOUNDS AND OXIME REACTIVATION

Organophosphates (OPs) exert their toxicity by inhibiting primarily acetylcholinesterase (AChE) and to a lesser extent butyrylcholinesterase (BChE). Binary mixtures of mammalian AChE and oximes of varying structure have been recently considered for treatment of OP poisoning as catalytic bioscavenger...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Küçükkilinç, Tuba, Cochran, Rory, Kalisiak, Jaroslaw, Garcia, Edzna, Valle, Anne, Amitai, Gabi, Radić, Zoran, Taylor, Palmer
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933076/
https://ncbi.nlm.nih.gov/pubmed/20382137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.03.050
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge