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Amphiphile regulation of ion channel function by changes in the bilayer spring constant
Many drugs are amphiphiles that, in addition to binding to a particular target protein, adsorb to cell membrane lipid bilayers and alter intrinsic bilayer physical properties (e.g., bilayer thickness, monolayer curvature, and elastic moduli). Such changes can modulate membrane protein function by al...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932597/ https://ncbi.nlm.nih.gov/pubmed/20713738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007455107 |
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