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Amphiphile regulation of ion channel function by changes in the bilayer spring constant
Many drugs are amphiphiles that, in addition to binding to a particular target protein, adsorb to cell membrane lipid bilayers and alter intrinsic bilayer physical properties (e.g., bilayer thickness, monolayer curvature, and elastic moduli). Such changes can modulate membrane protein function by al...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932597/ https://ncbi.nlm.nih.gov/pubmed/20713738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007455107 |
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