Regulation of Sodium Channel Function by Bilayer Elasticity: The Importance of Hydrophobic Coupling. Effects of Micelle-forming Amphiphiles and Cholesterol

Membrane proteins are regulated by the lipid bilayer composition. Specific lipid–protein interactions rarely are involved, which suggests that the regulation is due to changes in some general bilayer property (or properties). The hydrophobic coupling between a membrane-spanning protein and the surro...

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Main Authors: Lundbæk, Jens A., Birn, Pia, Hansen, Anker J., Søgaard, Rikke, Nielsen, Claus, Girshman, Jeffrey, Bruno, Michael J., Tape, Sonya E., Egebjerg, Jan, Greathouse, Denise V., Mattice, Gwendolyn L., Koeppe, Roger E., Andersen, Olaf S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234500/
https://ncbi.nlm.nih.gov/pubmed/15111647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308996
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