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A combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery
The application of RNA interference (RNAi), either in the clinic or laboratory, requires safe and effective delivery methods. Here we develop a combinatorial approach to synthesize a library of delivery vectors based on two lipid-like substrates with known siRNA delivery capabilities. Members of thi...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931596/ https://ncbi.nlm.nih.gov/pubmed/20715849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100041r |
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