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Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination

Studies have suggested that antigen receptor loci adopt contracted conformations to promote long-distance interactions between gene segments during V(D)J recombination. The Tcra/Tcrd locus is unique because it undergoes highly divergent Tcrd and Tcra recombination programs in CD4(−)CD8(−) double neg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shih, Han-Yu, Krangel, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931158/
https://ncbi.nlm.nih.gov/pubmed/20696701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100772
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