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Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node

The sympathetic nervous system increases heart rate by activating β adrenergic receptors and increasing cAMP levels in myocytes in the sinoatrial node. The molecular basis for this response is not well understood; however, the cardiac funny current (I(f)) is thought to be among the end effectors for...

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Bibliografski detalji
Glavni autori: Liao, Zhandi, Lockhead, Dean, Larson, Eric D., Proenza, Catherine
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931151/
https://ncbi.nlm.nih.gov/pubmed/20713547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010488
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